:root{--navy:#0E2A47;--deep:#091c31;--orange:#E57200;--paper:#FFFDF9;--mist:#EEF3F6;--ink:#17212C;--slate:#526171;--line:#D9DEE3;--teal:#3E7E76;--max:1220px}*{box-sizing:border-box}html{scroll-behavior:smooth}body{margin:0;background:var(--paper);color:var(--ink);font-family:"Open Sans",system-ui,-apple-system,"Segoe UI",sans-serif;line-height:1.65}img{display:block;max-width:100%}a{color:inherit;text-decoration:none}.wrap{width:min(var(--max),calc(100% - 40px));margin:auto}.skip{position:absolute;left:-999px}.skip:focus{left:8px;top:8px;z-index:99;padding:10px;background:#fff}.eye{color:var(--orange);font-size:.68rem;font-weight:850;letter-spacing:.15em;text-transform:uppercase}.title{margin:10px 0 0;color:var(--navy);font:500 clamp(2.464rem,4.224vw,4.4rem)/1.08 "Merriweather",Georgia,serif;letter-spacing:-.05em}.btn{display:inline-flex;align-items:center;justify-content:center;gap:9px;padding:13px 18px;border:1px solid currentColor;border-radius:999px;font-size:.72rem;font-weight:850;letter-spacing:.08em;text-transform:uppercase;transition:.2s ease}.btn:hover{transform:translateY(-2px)}
.utility{background:var(--deep);color:#DDE6EE;font-size:.72rem;letter-spacing:.04em}.utility .wrap{min-height:54px;display:flex;align-items:center;justify-content:space-between;gap:16px}.utility-right{display:flex;align-items:center;gap:18px}.utility a:hover{color:#fff}.uva-lockup{height:36px;width:auto;max-width:min(560px,70vw);object-fit:contain}header{position:sticky;top:0;z-index:40;background:rgba(255,255,255,.94);backdrop-filter:blur(14px);border-bottom:1px solid rgba(14,42,71,.08)}.nav{min-height:84px;display:flex;align-items:center;gap:24px}.brand{margin-right:auto;display:flex;align-items:center;gap:11px}.brand-logo{width:46px;height:46px;object-fit:contain;flex:0 0 46px}.brand-text{position:relative;padding-left:13px}.brand-text:before{content:"";position:absolute;left:0;top:1px;bottom:1px;width:3px;border-radius:99px;background:linear-gradient(to bottom,#3E8E86 0 50%,var(--orange) 50% 100%)}.brand-text strong{display:block;color:var(--navy);font-size:.94rem;font-weight:850;letter-spacing:-.02em;line-height:1.02;white-space:nowrap}.brand-text small{display:block;margin-top:4px;color:#3E7E76;font-size:.59rem;font-weight:600;line-height:1.2;white-space:nowrap}.nav-links{display:flex;align-items:center;gap:18px}.nav-links a{color:#304050;font-size:.86rem;font-weight:700}.nav-links a:hover,.nav-links a[aria-current="page"]{color:var(--orange)}.nav-cta{padding:.72rem 1rem;border-radius:999px;background:var(--orange);color:#fff!important}.menu-btn{display:none;border:0;background:none;color:var(--navy);font-size:1.4rem}
.hero{position:relative;overflow:hidden;padding:86px 0 54px;background-color:var(--deep);background-image:radial-gradient(circle at 10% 15%,rgba(229,114,0,.15),transparent 26%),linear-gradient(rgba(115,157,184,.07) 1px,transparent 1px),linear-gradient(90deg,rgba(115,157,184,.07) 1px,transparent 1px);background-size:auto,88px 88px,88px 88px;color:#fff}.hero-grid{display:grid;grid-template-columns:1.05fr .95fr;gap:70px;align-items:center}.hero h1{max-width:760px;margin:12px 0 22px;font:500 clamp(3.2rem,5.6vw,5.76rem)/1.04 "Merriweather",Georgia,serif;letter-spacing:-.06em}.hero h1 em{display:block;color:#F0A45F;font-style:normal}.hero-copy>p{max-width:650px;margin:0;color:#dce6ee;font-size:1.06rem}.hero-actions{display:flex;flex-wrap:wrap;gap:12px;margin-top:30px}.hero .btn.primary{border-color:var(--orange);background:var(--orange);color:#fff}.hero .btn.secondary{border-color:#ffffff78;color:#fff}.hero-media{position:relative;min-height:510px}.hero-media:before{content:"";position:absolute;inset:30px -36px -24px 45px;border:1px solid #e5720052;border-radius:42% 58% 24px 24px}.hero-media img{position:absolute;inset:0;width:100%;height:100%;object-fit:cover;object-position:center;border-radius:24px 110px 24px 24px;filter:saturate(.7)}
.trust{margin:22px 0;background:#fff;border:1px solid var(--line);border-radius:18px;overflow:hidden;box-shadow:0 10px 28px #091c3108}.trust-grid{display:grid;grid-template-columns:repeat(3,1fr)}.trust-item{padding:24px 28px}.trust-item+ .trust-item{border-left:1px solid var(--line)}.trust-item b{display:block;color:var(--navy);font-size:.94rem;font-weight:800;line-height:1.3}.trust-item span{display:block;margin-top:6px;color:var(--slate);font-size:.78rem;line-height:1.55}
section{padding:92px 0}.section-intro{display:grid;grid-template-columns:.82fr 1.18fr;gap:64px;align-items:end;margin-bottom:42px}.section-intro p{max-width:660px;margin:0;color:var(--slate);font-size:1.02rem}.studies{background:var(--paper)}.study-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:18px}.study{display:grid;grid-template-columns:210px 1fr;min-height:250px;overflow:hidden;border:1px solid var(--line);border-radius:20px;background:#fff;box-shadow:0 10px 28px #091c3109;transition:.25s ease}.study:hover{transform:translateY(-4px);box-shadow:0 18px 38px #091c3115}.study img{width:100%;height:100%;object-fit:cover}.study-body{display:flex;flex-direction:column;padding:26px}.status{align-self:flex-start;padding:5px 8px;border-radius:999px;background:#edf6f4;color:var(--teal);font-size:.57rem;font-weight:850;letter-spacing:.11em;text-transform:uppercase}.status.closed{background:#f1f2f4;color:#677481}.study h3{margin:13px 0 8px;color:var(--navy);font:500 1.349rem/1.1 "Merriweather",Georgia,serif}.study p{margin:0;color:var(--slate);font-size:.82rem}.study a{margin-top:auto;padding-top:18px;color:var(--orange);font-size:.68rem;font-weight:850;letter-spacing:.1em;text-transform:uppercase}.study a:hover{color:#b95700}.study.featured{grid-column:1/-1;grid-template-columns:minmax(300px,.78fr) 1.22fr;min-height:330px;border-top:4px solid var(--orange)}.study.featured .study-body{padding:32px}.study-meta{display:flex;align-items:center;gap:10px}.funding{color:var(--orange);font-size:.58rem;font-weight:850;letter-spacing:.11em;text-transform:uppercase}.study.featured h3{font-size:clamp(1.581rem,2.418vw,2.186rem)}.study-aims{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));margin:22px 0 4px;border-top:1px solid var(--line)}.study-aim{padding:16px 16px 0 0;color:var(--slate);font-size:.72rem;line-height:1.45}.study-aim:not(:last-child){margin-right:16px;border-right:1px solid var(--line)}.study-aim b{display:block;margin-bottom:4px;color:var(--orange);font-size:.58rem;letter-spacing:.1em;text-transform:uppercase}
.registry{padding:72px 0;background:var(--mist)}.registry-card{position:relative;display:grid;grid-template-columns:1.15fr .85fr;gap:52px;align-items:center;padding:48px;overflow:hidden;border-radius:28px;background:var(--navy);color:#fff}.registry-card:after{content:"";position:absolute;right:-110px;top:-130px;width:320px;height:320px;border:1px solid #ffffff20;border-radius:50%;box-shadow:0 0 0 55px #ffffff08}.registry-card h2{position:relative;z-index:1;margin:8px 0 14px;font:500 clamp(2.2rem,3.52vw,3.696rem)/1.08 "Merriweather",Georgia,serif;letter-spacing:-.04em}.registry-card p{position:relative;z-index:1;margin:0;color:#d7e1ea}.registry-action{position:relative;z-index:1}.registry-action .btn{width:100%;border-color:var(--orange);background:var(--orange);color:#fff}.registry-action small{display:block;margin-top:12px;color:#b9c8d4;font-size:.72rem;text-align:center}.registry-faq{width:100%;margin:0 auto;padding:0 48px 18px;border:1px solid var(--line);border-radius:18px;background:#fff;box-shadow:0 14px 34px #091c310c}.registry-faq:before{display:none}.registry-faq details{border-bottom:1px solid var(--line)}.registry-faq summary{position:relative;padding:22px 48px 22px 0;cursor:pointer;list-style:none;color:var(--navy);font-size:1.02rem;font-weight:800}.registry-faq summary::-webkit-details-marker{display:none}.registry-faq summary:after{content:"+";position:absolute;right:4px;top:50%;color:var(--teal);font-size:1.5rem;font-weight:400;line-height:1;transform:translateY(-50%);transition:transform .2s ease}.registry-faq details[open] summary:after{transform:translateY(-50%) rotate(45deg)}.registry-faq details[open] summary{color:var(--teal)}.registry-answer{max-width:820px;padding:4px 48px 26px 0;color:var(--slate);font-size:.95rem;line-height:1.7}.registry-answer p{margin:0}.registry-faq summary:focus-visible{outline:2px solid var(--orange);outline-offset:4px}
.mri{background:#fff}.mri-grid{display:grid;grid-template-columns:.9fr 1.1fr;gap:70px;align-items:center}.mri-media{position:relative}.mri-media img{width:100%;height:460px;object-fit:cover;border-radius:70px 20px 20px 20px}.mri-media:after{content:"";position:absolute;right:-18px;bottom:-18px;width:42%;height:42%;z-index:-1;border-radius:20px;background:#e5720015}.mri-copy p{color:var(--slate)}.mri-copy .btn{margin-top:16px;border-color:var(--navy);color:var(--navy)}
.contact{padding:76px 0;background:linear-gradient(125deg,#f3f7f9,#fff7ed)}.contact-card{display:grid;grid-template-columns:.75fr 1.25fr;gap:70px;align-items:start}.contact h2{margin:8px 0 0;color:var(--navy);font:500 clamp(2.2rem,3.52vw,3.52rem)/1.08 "Merriweather",Georgia,serif}.contact-details{display:grid;grid-template-columns:repeat(2,1fr);border-top:1px solid var(--line)}.contact-item{padding:22px 24px 0 0}.contact-item+ .contact-item{padding-left:24px;border-left:1px solid var(--line)}.contact-item b{display:block;margin-bottom:5px;color:var(--orange);font-size:.65rem;letter-spacing:.12em;text-transform:uppercase}.contact-item span,.contact-item a{color:var(--navy);font-size:.9rem}.contact-item a:hover{color:var(--orange)}
footer{background:var(--deep);color:#DBE4EC;padding:56px 0 26px}.footer-grid{display:grid;grid-template-columns:1.35fr 1fr 1fr;gap:60px}.footer-brand{display:flex;align-items:center;gap:14px;margin-bottom:14px}.footer-logo{display:block;width:min(400px,100%);height:auto;object-fit:contain}.footer-eyebrow{color:#F0A45F;text-transform:uppercase;letter-spacing:.14em;font-size:.68rem;font-weight:800;margin-bottom:10px}.footer-links a{display:block;padding:4px 0;font-size:.86rem;color:#D7E1EA}.footer-links a:hover{color:#fff}.copyright{border-top:1px solid rgba(255,255,255,.12);margin-top:28px;padding-top:18px;font-size:.76rem;color:#A5B4C1;display:flex;justify-content:space-between;gap:20px;flex-wrap:wrap}
@media(max-width:980px){.menu-btn{display:block}.nav-links{display:none;position:absolute;left:0;right:0;top:84px;padding:18px 20px 24px;background:var(--paper);border-bottom:1px solid var(--line);flex-direction:column;align-items:flex-start}.nav-links.open{display:flex}.hero-grid,.section-intro,.registry-card,.mri-grid,.contact-card{grid-template-columns:1fr}.hero-media{min-height:430px}.study{grid-template-columns:170px 1fr}.footer-grid{grid-template-columns:1fr}}@media(max-width:680px){.wrap{width:calc(100% - 28px)}.utility-right{display:none}.hero{padding:62px 0 44px}.hero h1{font-size:2.96rem}.hero-media{min-height:360px}.trust-grid,.study-grid,.contact-details{grid-template-columns:1fr}.trust-item+ .trust-item,.contact-item+ .contact-item{padding-left:0;border-left:0;border-top:1px solid var(--line)}.study,.study.featured{grid-template-columns:1fr}.study img,.study.featured img{height:210px}.study.featured .study-body{padding:26px}.study-aims{grid-template-columns:1fr}.study-aim,.study-aim:not(:last-child){margin-right:0;padding:12px 0;border-right:0;border-bottom:1px solid var(--line)}.study-aim:last-child{border-bottom:0}.registry-card{padding:34px 24px}.registry-faq{width:100%}.registry-faq{padding:0 24px 14px}.registry-answer{padding-left:0;padding-right:24px}.mri-media img{height:360px}.footer-grid{grid-template-columns:1fr}.copyright{flex-direction:column}}

.study-eligibility{margin:8px 0 0;padding-left:18px}.study-eligibility li+li{margin-top:8px}.study-eligibility li::marker{color:var(--orange,#E57200)}

.survey-modal-card{cursor:pointer}
.survey-details-button{display:inline-block;padding:0;margin-top:22px;border:0;background:none;color:var(--orange,#E57200);font:800 .72rem/1.5 inherit;font-family:inherit;font-size:.72rem;font-weight:800;letter-spacing:.06em;text-transform:uppercase;text-align:left;cursor:pointer}
.survey-details-button:focus-visible,.survey-dialog-close:focus-visible{outline:2px solid #e57200;outline-offset:5px}
.study-details-dialog{width:min(760px,calc(100% - 32px));max-height:85vh;max-height:85dvh;padding:0;border:1px solid #d5e1e3;border-top:4px solid #e57200;border-radius:20px;background:#fffdf9;color:#0e2a47;box-shadow:0 28px 90px #091e3060;overflow:auto}
.study-details-dialog::backdrop{background:rgba(9,30,48,.72);backdrop-filter:blur(4px)}
.survey-dialog-content{position:relative;padding:38px}
.survey-dialog-close{position:absolute;right:16px;top:14px;width:36px;height:36px;border:1px solid #c9d8db;border-radius:50%;background:#fff;color:#0e2a47;font-size:1.6rem;cursor:pointer}
.study-details-dialog h2{font:400 clamp(1.584rem,3.52vw,2.288rem)/1.12 "Merriweather",Georgia,serif;margin:18px 32px 14px 0}
.study-details-dialog h3{font:600 1.116rem/1.3 "Merriweather",Georgia,serif;margin:24px 0 8px}
.study-details-dialog p{color:#526171;font-size:.95rem;line-height:1.75;margin:0 0 16px}
.survey-dialog-facts{display:grid;grid-template-columns:1fr 1fr 1fr;gap:20px;padding:20px;background:#eef5f3;border-radius:12px;margin:22px 0}
.survey-dialog-facts dt{font-size:.7rem;font-weight:800;text-transform:uppercase;letter-spacing:.08em;color:#39736f;margin-bottom:7px}
.survey-dialog-facts dd{margin:0;font-size:.87rem;line-height:1.6}
.survey-original-link{display:inline-block;color:#39736f;text-decoration:underline;font-size:.85rem;text-underline-offset:3px}
body.survey-dialog-open{overflow:hidden}
@media(max-width:550px){.survey-dialog-content{padding:28px 22px}.survey-dialog-facts{grid-template-columns:1fr;gap:14px}}